Cancer Vaccine Biotech Cimcure Raises € 5 Million In Seed Round Investment Led By Positron Ventures
06/07/22, 3:00 AM
Location
amsterdamMoney raised
€5 million
Round Type
seed
CimCure, a biotech spin-off of Amsterdam UMC, focusing on the development of a novel vaccine-based cancer immunotherapy through its Immune-Boost (iBoost) technology, today announced that it has raised little over € 5 million in a financing Seed Round led by Dutch VC Positron Ventures. The round was supported by several investors with deep industry knowledge, including the investment vehicle of Tom Würdinger, professor at Amsterdam UMC. With the proceeds of this Seed Round CimCure will further advance the vaccine up until phase 1-2 clinical studies in humans. Dutch vaccine CDMO Intravacc will be CimCure's partner for the development and production of the lead compound.
Company Info
Location
amsterdam, new york, united states
Additional Info
CimCure develops cancer vaccines through its proprietary Immune-Boost (iBoost) technology of targeted conjugate vaccines. The company has identified specific targets in the tumor vasculature. Eradication of tumor blood vessels and inhibition of their growth will lead to inhibition of cancer growth. This is an attractive approach for treatment of cancer. However, past and current angiostatic drugs are known for rapid induction of drug resistance and loss of effectiveness, due to intervention in tumor-produced growth factors or their receptors. CimCure's approach directly targets the tumor blood vessels, which efficiently attenuates tumor growth directly and does not induce resistance. An additional advantage of targeting blood vessels is that the barrier function of the tumor vasculature for leukocytes can be overcome (Huinen et al, Nature Reviews Clinical Oncology, 2021).