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Centivax And U.S. Naval Medical Research Center Announce Strategic Partnership To Initiate Clinical Development Of A Broad-Spectrum Injectable For Covid-19, With $4.2M From The Henry Jackson Foundation

Jun 02, 2021•over 4 years ago
San Francisco

Description

Centivax Inc. announced today that it has entered into a strategic partnership with the U.S. Naval Medical Research Center (NMRC) for Phase I clinical development of Centi-B9, Centivax's SARS-CoV-2 broad-spectrum injectable antibody therapeutic and prophylactic. Centi-B9 has been engineered to broadly neutralize the mutated emerging coronavirus variants, with demonstrated broad-spectrum reactivity against 99.5% of all coronavirus variants in the U.S.A, and over 98% of coronavirus variants globally, including critical mutations found in the UK B.1.1.7, South African B.1.351, Brazilian P.1, New York B.1.526 and California B.1.429 strains

Company Information

Company

Centivax

Location

San Francisco, California, United States

About

Centivax is a clinical stage company that leverages our computational bioengineering platforms to solve drugability and manufacturability problems of validated but challenging drug targets. Most of our targets are complex because of mutation diversity. Our broad therapeutic portfolio of two programs entering clinical stage development by August 2021 and thirteen pre-clinical programs scheduled to complete pre-clinical and enter clinical development in 2023, 2024, and 2025. The portfolio includes broad-spectrum vaccines and broadly neutralizing antibodies to emerging infectious diseases and rapidly mutating viruses including SARS-CoV-2, influenza and HIV; antibodies and vaccines against diverse and multi-drug resistant bacteria including MRSA, Klebsiella, Pseudomonas, and Acinetobacter; therapeutic interventions for highly mutable cancers and immune-oncology targets; an optimized antibody against the auto-immune disorder target CXCR5; and broad-spectrum antibodies against the major toxins found in all snake venom. Our competitive advantage is our intellectual property and engineering expertise in broad spectrum vaccines and broadly neutralizing antibodies that can confront highly diverse targets, including emerging infectious pathogens. Our technologies have provided the means for both vaccines and antibodies to be delivered through highly convenient modes of injection, such as intramuscular and subcutaneous routes of administration in non-hospitalized settings. SOURCE Centivax