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Alaya.bio Expands Collaboration with Columbia University for in situ CAR-T Therapy

Alaya.bio Expands Collaboration with Columbia University for in situ CAR-T Therapy

01/21/25, 12:50 PM
Industry
therapeutics
biotechnology
manufacturing
Type
partnership
Alaya.bio has announced an expanded collaboration with Michel Sadelain, M.D. Ph.D., and his research team at Columbia University. This partnership aims to intensify the development of Alaya.bio's proprietary polymeric delivery platform for in situ CAR-T cell therapy, building on the successful collaboration initiated at the Memorial Sloan Kettering Cancer Center.

Company Info

Company
Alaya.bio
Additional Info
Alaya.bio is a pioneering biotechnology company dedicated to advancing in vivo gene delivery platform, particularly in the field of CAR T cell immunotherapy. The proprietary technology relies on a targeting polymeric nanoparticle comprised of a lentiviral vector coated by a biodegradable polymer allowing the targeting and transduction of T-cells. The platform technology is designed to enhance the transduction efficiency of quiescent cells, including T cells, NK cells, and stem cells. It can be used either ex vivo (as part of rapid manufacturing processes) or in vivo (in situ transduction within the patient after systemic administration).